Vitamin B-12 With Reflex To MMA

Test Code: TD_2827
CPT Code(s): 82607

$30

Test Details

Alternative Name(s)

Vitamin B-12 with reflex to methylmalonic acid (MMA)

Test Includes

Vitamin B-12 With Reflex To MMA

Methodology

Roche COBAS Electrochemiluminescent Immunoassay (ECLIA)

Rejection Criteria

Hemolysis
Allow only one freeze/thaw cycle

Reference Range(s)

200-950 pg/mL
Will reflex to methylmalonic Acid when result is less than 300 pg/mL.
Additional charges will apply

Specimen Requirements

Preferred Specimen

Serum Separator Tube

Minimum Volume

1 mL Serum in each of 2 tubes

Sample Stability

1 day room temperature
4 days refrigerated
56 days frozen

Transport Temperature

1 sample refrigerated
1 sample Critical Frozen (CFZ)

Collection Instructions

This test requires submission of 2 separate serum samples.
1. 2 mL Serum. Allow SST to clot in an upright position for at least 30 minutes, then centfifuge sample within 2 hours of collection. Refrigerate.
Note: Do not collect samples from patients receiving therapy with high biotin doses (>5 mg/day) until at least 8 hours following the last biotin administration.
2. 2 mL serum. Allow SST to clot in an upright position for at least 30 minutes, then centrifuge sample within
2 hours of collection. Transfer serum to a plastic transport tube. Clearly label tube as serum. Freeze. Critical Frozen (CFZ).
When multiple tests are ordered, submit separate tubes for this test.

Alternative Specimen

This test requires submission of 2 separate serum samples.
1. 2 mL serum from a plain red top tube. Allow sample to clot in an upright position for at least 60 minutes, then centrifuge sample and transfer serum to a plastic transport tube within 2 hours of collection. Clearly label tube as serum from a plain red top tube. Refrigerate.
Note: Do not collect samples from patients receiving therapy with high biotin doses (>5 mg/day) until at least 8 hours following the last biotin administration.
2. 2 mL serum from a plain red top tube. Allow sample to clot in an upright position for at least 60 minutes, then centrifuge sample and transfer serum to a plastic tube within 2 hours of collection. Clearly label tube as serum from a plain red top tube. Freeze. Critical Frozen (CFZ).
When multiple tests are ordered, submit separate tubes for this test.