Venlafaxine, Serum

Test Code: TD_5968

CPT Code(s): 80338

Test Details

Alternative Name(s)

Effexor
Effexor xr
Pristiq
Venlafaxide

Test Includes

Venlafaxine, Serum

Methodology

Liquid chromatography-tandem mass spectrometry (LC-MS/MS)

Rejection Criteria

Samples collected in separator tubes
Citrate (light blue top) plasma
ACD or SPS (yellow top) plasma
Whole blood

Reference Range(s)

Therapeutic Range : Venlafaxine + O-Desmethylvenlafaxine: 195-400 NG/ML
Toxic: Venlafaxine + O-Desmethylvenlafaxine: >800 NG/ML

Specimen Requirements

Preferred Specimen

Plain red top tube

Minimum Volume

0.5 mL serum or plasma

Sample Stability

2 weeks room temperature
2 weeks refrigerated
2 weeks frozen

Transport Temperature

Refrigerated

Collection Instructions

Allow sample to clot in an upright position for at least 60 minutes, then centrifuge sample and transfer serum to a plastic transport tube within 2 hours of collection. Clearly label tube as serum from a plain red top tube. Refrigerate.
Note: Collect pre-dose (trough) sample at steady-state concentration.

Alternative Specimen

1 mL EDTA (lavender top) plasma. Centrifuge sample and separate plasma from cells within 2 hours of collection. Transfer plasma to a plastic transport tube. Clearly label tube as EDTA or heparin plasma. Refrigerate. Note: Collect pre-dose (trough) sample at steady-state concentration.