Methylmalonic Acid, Serum

Test Code: TD_4291

CPT Code(s): 83921

$49

Test Details

Alternative Name(s)

MMA
Acid, Methylmalonic

Test Includes

MMA

Methodology

Liquid chromatography-tandem mass spectrometry (LC-MS/MS)

Rejection Criteria

room temperature samples

Reference Range(s)

<0.41 UMOL/L

Specimen Requirements

Preferred Specimen

Serum Separator Tube

Minimum Volume

0.3 mL serum or plasma

Sample Stability

Unacceptable room temperature
5 days refrigerated
1 month frozen

Transport Temperature

Frozen

Collection Instructions

Allow SST to clot in an upright position for
at least 30 minutes, then centrifuge sample within 2 hours
of collection. Transfer serum to a plastic transport tube.
Clearly label tube as serum. Freeze.
Critical Frozen (CFZ). When multiple tests are ordered,
submit separate tube for this test.

Alternative Specimen

2 mL serum from a plain red top tube. Allow sample to clot in an upright position for at least 60 minutes, then centrifuge sample and transfer serum to a plastic transport tube within 2 hours of collection. Clearly label tube as serum from a plain red top tube. Freeze. Critical Frozen (CFZ). When multiple tests are ordered, submit separate tube for this test.
2 mL EDTA (lavender top) or heparin (green top) plasma. centrifuge sample and separate plasma from cells immediately. Transfer plasma to a plastic transport tube. Clearly label tube as EDTA or heparin plasma. Freeze. Critical Frozen (CFZ). When multiple tests are ordered, submit separate tube for this test.