Autoimmune Antibody Profile

Test Code: TD_4268

CPT Code(s): 86235 X8, 86376, 86160 X2, 86431, 86225, 86200, 83516

$329

Test Details

Alternative Name(s)

Autoantibody panel

Test Includes

Rheumatoid Factor, Quant
Complement C3
Complement c4
Sjogren’s SS-A antibody
Sjogren’s SS-B antibody
Smith (Sm) antibody
RNP antibody
DsDNA antibody
Ribosomal P antibody
Thyroid peroxidase AB
SCL-70 antibody
Centromere B antibody
Jo-1 antibody
Chromatin antibody
CCP IgG

Methodology

Autoimmune antibodies: multiplex flow immunoassay Thyroid peroxidase AB: Roche Electrochemiluminescence Immunoassay (ECLIA)

Rejection Criteria

Hemolysis
Avoid repeated freeze/thaw cycles

Reference Range(s)

By Report

Specimen Requirements

Preferred Specimen

Serum Separator Tube

Minimum Volume

4 mL serum

Sample Stability

Autoimmune Antibodies: 1 day room temperature; 1 week refrigerated; 1 month frozen
Thyroid peroxidase AB: 8 days room temperature; 8 days refrigerated; 6 months frozen
Complement c3: 4 days room temperature; 8 days refrigerated; 8 days frozen
Complement c4: 2 days room temperature; 8 days refrigerated 3 months frozen
Rheumatoid factor, quant: 1 day room temperature; 8 days refrigerated; 3 months frozen

Transport Temperature

Refrigerated

Collection Instructions

Collect 2 serum separator tubes. Allow tubes to clot in an upright position for at least 30 minutes, then centrifuge samples within 2 hours of collection. Transfer serum to a plastic transport tube. Refrigerate.
Note: Do not collect samples from patients receiving therapy with high biotin doses (>5 mg/day) until at least 8 hours following the last biotin administration.

Alternative Specimen

Collect 2 plain red top tubes. Allow sample to clot in an upright position for at least 60 minutes, then centrifuge sample and transfer serum to a plastic transport tube within 2 hours of collection. Clearly label tubes as serum from a plain red top tube. Refrigerate. Note: Do not collect samples from patients receiving therapy with high biotin doses (>5 mg/day) until at least 8 hours following the last biotin administration.